According to the National Association for Continence, more than one-third of adults over the age of 30 get up twice or more a night to urinate. While most who deal with this are over the age of 60, it can occur at any age. Getting up to go multiple times per night can cause a lack of sleep, which can lead to stress, tiredness, and irritability and can have a negative impact on health and well being in general. Survey data from the European Association of Urology showed a “strong negative impact on utility, work productivity, and health-related quality of life, which increases with the severity of the condition.”
Men and women may experience nocturia for different reasons: In women, in may be as a result of childbirth, menopause, or pelvic organ prolapse. In men, it can be related to benign prostatic hyperplasia (BPH), also known as enlarged prostrate. Other factors that apply to both genders include behavioral patterns/conditioning, diuretic medications, caffeine, alcohol, overactive bladder treatment, excessive fluids before bedtime, diminished nocturnal bladder capacity, or urinary tract infection.
It may also be the symptom of another condition that may cause the production of too much urine, too much concentrated urine, or the bladder to hold less than it should, such as diabetes, high blood pressure, heart disease, vascular disease, restless leg syndrome, bladder or prostate tumors, interstitial cystitis, liver failure, neurologic diseases like Alzheimer’s and Parkinson’s, or sleep disorders such as insomnia or sleep apnea. Many times, if the underlying condition can be treated, this will relieve nocturia symptoms as well.
Behavioral modifications that may help with the condition include limiting the intake of fluids in the evening; taking afternoon naps to help reduce the fluid buildup; leg elevation; and compression stockings. One study, conducted by a group of researchers from Nagasaki University, found that a reduction in sodium intake led to a reduction in urination frequency.
According to the Cleveland Clinic, current pharmaceutical treatments include anti-cholinergic medications, which reduce symptoms of an overactive bladder; diuretics that assist in regulating urine production; and medications which help the kidneys produce less urine. Some of these medications come with side effects, and some may lead to fluid retention, worsening other conditions.
Increased research funding and participation in clinical studies is the best way to discover new and effective treatments for nocturia. Meridien Research has nocturia research studies that are enrolling now. For more information or to see if you or someone you know may qualify to participate, please contact us today at 727-347-8839 or visit our study pages today.