Dr. Gigi Lefebvre and her team at Meridien Research in St. Petersburg, Florida conduct dozens of studies each year and many focus on dermatology conditions, which are those that involve the skin. Studies often concentrate on acne for adolescents and rosacea and actinic keratoses for adults.
Acne is a common and frustrating skin condition for teens as well as some adults. It develops when the body produces excessive amounts of sebum (the oily, waxy substance on the skin) and a buildup of dead skin which clogs pores and allows bacteria to thrive.
Though acne can involve many areas of the body, Meridien Research usually conducts clinical research trials involving acne on the face, and generally studies moderate to severe acne, but rarely cystic acne.
Topical therapies are typically used to treat this type of acne. There are many generic topical medications being studied, as many acne medications will be losing their patents soon. This research is therefore necessary to get FDA approval for these more affordable generic acne medications. Meridien also studies new medications with novel modes of action, as not all patients respond to the medications currently available on the market. This cutting edge acne research offers adolescents and teens the opportunity to learn more about their skin condition and to try medications to which they otherwise might not have access.
Rosacea looks like acne, although this disorder typically presents in adults over 30 years old. The exact cause is unknown, but the symptoms include:
- Facial redness on the cheeks and nose (often with blood vessels becoming enlarged and thus more visible),
- Thickening of the skin (often resulting in an enlarged nose),
- Bumps and pimples, and
- Eye irritation.
Treatment involves avoiding irritants such as spicy foods, hot drinks, alcohol, chocolate, red wine, and exposure to excessive heat or cold. Medications are of some benefit especially for the bumps and pimples, thus Meridien Research conducts trials of oral medications as well as topical creams and gels which might help.
Florida residents have to constantly be aware of exposure to the sun. Over time, sun damaged skin can develop scaly or crusty growths that appears on areas of the body frequently exposed to direct sunlight. These lesions are called actinic keratoses (AK’s), and it is estimated that more than 58 million Americans have them. Though AK’s are benign, about 10% of them will change into squamous cell cialis definition cancer (SCCA) of the skin. Though not as deadly as melanoma, SCCA is a potentially deadly cancer as it can metastasize to other parts of the body.
“We typically treat actinic keratoses with topical medication,” explained Dr. Gigi C. Lefebvre, Principal Investigator at Meridien Research. “These lesions if left untreated can become cancer, thus treatment of actinic keratoses prohibits the development of cancer, and makes surgery, radiation, and chemotherapy unnecessary. It is great preventative medicine and certainly cost-effective.”
A Need for Research
The skin is the largest organ of the human body. We often take it for granted, but diseases of the skin can be a cause for embarrassment and low self-esteem, and can even be life-threatening. Meridien Research strives to advance knowledge of these diseases and aims to offer patients options for treatment both old and new.
If you would like more information regarding the clinical research studies being conducted at Meridien Research, please call 888-777-8839 or, go to the Studies page of our website, as we cialis generique have 6 sites located throughout the state of Florida.